CA3124834A1 — Methods of administration for highly water-soluble salts of a short acting phenylalkylamine calcium channel blocker
Assigned to Milestone Pharmaceuticals Inc · Expires 2023-01-15 · 3y expired
What this patent protects
The present invention is related to use of a therapeutically effective amount of a compound having a structure according to the formula: (see formula I) for treating cardiac arrhythmia, angina, or a migraine in a patient in need thereof, where compound l is formulated for nasal a…
USPTO Abstract
The present invention is related to use of a therapeutically effective amount of a compound having a structure according to the formula: (see formula I) for treating cardiac arrhythmia, angina, or a migraine in a patient in need thereof, where compound l is formulated for nasal administration to the patient in (i) a first dose, and (ii) a second dose of an aqueous composition comprising a pharmaceutically acceptable acetate or methanesulfonate salt of compound l, or a racemate or enantiomer thereof, wherein the acetate or methanesulfonate salt of compound l , or the racemate or enantiomer thereof, is dissolved in the aqueous composition at a concentration of 350 mg/mL~ 50 mg/mL, and wherein the second dose of the compound is to be administered between 5 minutes and 25 minutes after the first dose.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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