CA3121449A1 — Nucleic acid conjugate
Assigned to Kyowa Kirin Co Ltd · Expires 2020-06-04 · 6y expired
What this patent protects
The present invention provides a nucleic acid complex represented by formula 1. Formula 1: (In formula 1, X is a double-stranded nucleic acid that comprises a sense strand and an antisense strand and that includes a duplex region of at least 11 base pairs; the double-stranded nuc…
USPTO Abstract
The present invention provides a nucleic acid complex represented by formula 1. Formula 1: (In formula 1, X is a double-stranded nucleic acid that comprises a sense strand and an antisense strand and that includes a duplex region of at least 11 base pairs; the double-stranded nucleic acid is complementary with any of the target APCS mRNA sequences listed in Tables 1-1 to 1-13 in an oligonucleotide strand having a strand length of 17-30 nucleotides in the antisense strand, and the 3' end or 5' end of the sense strand bonds to S3; L1 and L2 each independently represent a sugar ligand; S1, S2, and S3 each independently represent a linker.)
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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