CA3093645A1 — Heterobifunctional compound having monodispersed polyethylene glycol in main chain and side chain

USPTO Abstract

The present invention is a heterobifunctional monodispersed polyethylene glycol represented by formula (1). (In the formula, each of X1 and Y1 represents an atomic group which contains a functional group that forms a covalent bond by reacting with a functional group that is present in a biologically functional molecule, and the functional group contained in X1 and the functional group contained in Y1 are different from each other; R1 represents a hydrocarbon group having 1-7 carbon atoms, or a hydrogen atom; n represents an integer of 3-72; l represents an integer of 2-72; A1 represents -L1-(CH2)m1- or -L1-(CH2)m1-L2-(CH2)m2-, wherein L1 represents a specific bond or a single bond, L2 represents a specific bond, and each of m1 and m2 independently represents an integer of 1-5; B1 represents -L3-(CH2)m3-, -L3-(CH2)m3-L4-(CH2)m4- or a single bond, wherein L3 represents an amide bond or a single bond, L4 represents a specific bond, and each of m3 and m4 independently represents an integer of 1-5; and C1 represents -L5-(CH2)m5-, -O-CH2- or a single bond, wherein L5 represents a specific bond or a single bond, and m5 represents an integer of 1-5.)