CA3061421A1 — Method of providing contraception in a patient

USPTO Abstract

A method of providing contraception in a patient is disclosed. The method comprises: administering daily an active pharmaceutical composition comprising 2 mg to 6 mg drospirenone and one or more pharmaceutically-acceptable excipients to said patient; wherein the dissolution rate of said drospirenone in said pharmaceutical composition is such that when subjected to an in vitro dissolution test according to the USP XXIII Paddle Method: no more than 50% of said drospirenone initially present in said pharmaceutical composition is dissolved within 30 minutes, and at least 50% of said drospirenone is dissolved in a time range from 3 hours to 4 hours; and wherein said pharmaceutical composition does not contain an estrogen. The method allows reliability and efficiency as traditional contraceptive method with, for instance, less side-effects on cardiovascular system.