CA3033180A1 — Pharmaceutical compositions containing substituted polycyclic pyridone derivatives and prodrug thereof

USPTO Abstract

The present invention provides a pharmaceutical composition containing the following compound, which has an antiviral action. (P is a hydrogen atom or a group that forms a prodrug; A1 is CR1AR1B, S, or O; A2 is CR2AR2B, S, or O; A3 is CR3AR3B, S, or O; A4 each independently are CR4AR4B, S, or O; the number of heteroatoms of A1, A2, A3, A4, nitrogen atoms adjacent to A1, and ring constituent atoms of a ring configured from nitrogen atoms adjacent to A4 is 1 or 2; R1A and R1B each independently are hydrogen, halogen, alkyl, etc.; R2A and R2B each independently are hydrogen, halogen, alkyl, etc.; R3A and R3B each independently are hydrogen, halogen, alkyl, etc.; R4A and R4B each independently are hydrogen, halogen, alkyl, etc.; R3A and R3B together may form a non-aromatic carbocycle or non-aromatic heterocycle; R1 is a fluorine atom; m is an integer of 1-2; and n is an integer of 1-2)