CA Patent

CA3003589C — Dendrimer compositions and methods for treatment of peroxisomal disorders and leukodystrophies

Assigned to Johns Hopkins University · Expires 2021-12-07 · 4y expired

What this patent protects

Compositions and methods for treating, alleviating, and/or preventing one or more symptoms associated with axonal degeneration in individuals in need thereof, such as individuals with peroxisomal disorders and leukodystrophies include one or more poly(amidoamine) dendrimers G1- G…

USPTO Abstract

Compositions and methods for treating, alleviating, and/or preventing one or more symptoms associated with axonal degeneration in individuals in need thereof, such as individuals with peroxisomal disorders and leukodystrophies include one or more poly(amidoamine) dendrimers G1- G10, preferably G4-G6, complexed with therapeutic, prophylactic and/or diagnostic agent in an effective amount to treat, and/or prevent one or more symptoms associated with axonal degeneration are provided. Compositions are particularly suited for targeted delivery of therapeutics to the affected spinal neurons and may contain one or more additional targeting moieties.

Drugs covered by this patent

Patent Metadata

Patent number
CA3003589C
Jurisdiction
CA
Classification
—
Expires
2021-12-07
Drug substance claim
No
Drug product claim
No
Assignee
Johns Hopkins University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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