CA2960392A1 — Process to prepare 5,7-dichloro-3,4-dihydro-1h-isoquinolin-6-carboxylic acid using a continuous flow carboxylation reaction
Assigned to Novartis AG · Expires 2016-03-31 · 10y expired
What this patent protects
The present invention is related to a two-step carboxylation reaction of an aryl group, for example by reacting a compound of Formula II: using continuous flow reaction conditions to obtain a compound of Formula I: This process permits large scale synthesis of useful reaction pro…
USPTO Abstract
The present invention is related to a two-step carboxylation reaction of an aryl group, for example by reacting a compound of Formula II: using continuous flow reaction conditions to obtain a compound of Formula I: This process permits large scale synthesis of useful reaction products in high yield.
Drugs covered by this patent
- Xiidra (LIFITEGRAST) · Bausch Health
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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