CA Patent

CA2955495A1 — High dosage strength tablets of rucaparib

Assigned to Pharma and Schweiz GmbH · Expires 2016-02-25 · 10y expired

What this patent protects

A tablet including high dosage of 8-fluoro-2-(4-[(methylamino)methyl]phenyl)-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one camsylate salt has been disclosed. The invention is directed to high dosage strength tablets of rucaparib. In some embodiments, the tablet includes 45-9…

USPTO Abstract

A tablet including high dosage of 8-fluoro-2-(4-[(methylamino)methyl]phenyl)-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one camsylate salt has been disclosed. The invention is directed to high dosage strength tablets of rucaparib. In some embodiments, the tablet includes 45-90% w/w rucaparib camsylate. In some embodiments, the dry granulated tablet includes 45-90% w/w rucaparib camsylate. One such embodiment is a tablet containing at least 200 mg rucaparib. Another embodiment is a tablet containing at least 300 mg rucaparib. The invention also relates to the use of the tablet in the treatment of a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity, including, for example, cancer.

Drugs covered by this patent

Patent Metadata

Patent number
CA2955495A1
Jurisdiction
CA
Classification
Expires
2016-02-25
Drug substance claim
No
Drug product claim
No
Assignee
Pharma and Schweiz GmbH
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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