CA2916564C — Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
Assigned to Global Blood Therapeutics Inc · Expires 2023-02-28 · 3y expired
What this patent protects
Disclosed are crystalline free base ansolvate and solvate forms of 2-hydroxy-6-((2-1-isopropy1-1H-pyrazol-5-yl)pyridine-3-yl)methoxy)benzaldehyde (or Compound 1), such as the free base Form I, Form 11 and Material N. These forms are used to prepare the solid crystalline free base…
USPTO Abstract
Disclosed are crystalline free base ansolvate and solvate forms of 2-hydroxy-6-((2-1-isopropy1-1H-pyrazol-5-yl)pyridine-3-yl)methoxy)benzaldehyde (or Compound 1), such as the free base Form I, Form 11 and Material N. These forms are used to prepare the solid crystalline free base of Compound 1 which may be used to increase oxygen affinity of hemoglobin in a subject, treating a disorder mediated by hemoglobin, or treating sickle cell disease.
Drugs covered by this patent
- Oxbryta (voxelotor) · Global Blood Theraps
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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