CA2906732C — Lipid nanoparticles for transfection and related methods
Assigned to University of British Columbia · Expires 2023-08-08 · 3y expired
What this patent protects
ABSTRACT Transfection reagent compositions are provided, comprising (a) 1,17-bis(2-octylcyclopropyl)heptadecan-9-y1-4-(dimethylamino)butanoate, or pharmaceutically acceptable salts thereof; (b) 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC); (c) cholesterol; and (d) one or mor…
USPTO Abstract
ABSTRACT Transfection reagent compositions are provided, comprising (a) 1,17-bis(2-octylcyclopropyl)heptadecan-9-y1-4-(dimethylamino)butanoate, or pharmaceutically acceptable salts thereof; (b) 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC); (c) cholesterol; and (d) one or more surfactants selected from polyoxyethylene (20) oleyl ether, polyoxyethylene (23) lauryl ether, or polyethylene (40) stearate. Lipid nanoparticles prepared from the transfection reagent composition, kits that include the transfection reagent composition, and methods for making and using lipid nanoparticles prepared from the transfection reagent composition are also provided. CAN_DMS: \138063613\1 Date Recue/Date Received 2021-02-23
Drugs covered by this patent
- Onpattro (PATISIRAN SODIUM) · Alnylam Pharmaceuticals
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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