CA2898514A1 — Synthetic peptide amides and dimers thereof
Assigned to Tvardi Therapeutics Inc · Expires 2008-05-22 · 18y expired
What this patent protects
The invention relates to synthetic peptide amide dimer ligands of the kappa opioid receptor and particularly to synthetic peptide amide dimer agonists of the kappa opioid receptor that exhibit low P450 CYP inhibition and low penetration into the brain. The synthetic peptide amide…
USPTO Abstract
The invention relates to synthetic peptide amide dimer ligands of the kappa opioid receptor and particularly to synthetic peptide amide dimer agonists of the kappa opioid receptor that exhibit low P450 CYP inhibition and low penetration into the brain. The synthetic peptide amide dimers of the invention conform to the structure: (See above Formula) wherein G is (See above Formula) The synthetic peptide amide dimer compounds are useful in the prophylaxis and treatment of pain and inflammation associated with a variety of diseases and conditions including pain and inflammation.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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