CA2771011A1 — Crystalline compound of 7-[(3r)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
Assigned to Sandoz AG · Expires 2011-02-17 · 15y expired
What this patent protects
The present invention relates to a crystalline compound of 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine (INN:Sitagliptin) of the formula (1), having fumaric acid or a hydrate thereof, wherein the molar …
USPTO Abstract
The present invention relates to a crystalline compound of 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine (INN:Sitagliptin) of the formula (1), having fumaric acid or a hydrate thereof, wherein the molar ratio of the compound of the formula (1) to fumaric acid is 1:0.6 to 1:1.3, and a method for the production thereof.
Drugs covered by this patent
- Steglatro (ERTUGLIFLOZIN) · Merck & Co.
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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