CA2760174A1 — Protein kinase inhibitors and uses thereof
Assigned to Pharmascience Inc · Expires 2013-06-01 · 13y expired
What this patent protects
The present invention relates to a new class of 5-aryl-5H-pyrrolo[3,2-d]pyrimidin-4-amines which contain 6,7-fused cycloalkyl and heterocycloalkyl ring systems. Compounds of this class have been found to be effective inhibitors of protein kinases: including members of the SRC an…
USPTO Abstract
The present invention relates to a new class of 5-aryl-5H-pyrrolo[3,2-d]pyrimidin-4-amines which contain 6,7-fused cycloalkyl and heterocycloalkyl ring systems. Compounds of this class have been found to be effective inhibitors of protein kinases: including members of the SRC and Tec kinase families. These compounds demonstrate the requisite physiochemical properties for use as pharmaceutical agents for the treatment of various proliferative, inflammatory and autoimmune diseases such as, but not limited to, cancer, arthritis, MS and the like.
Drugs covered by this patent
- Calquence (ACALABRUTINIB) · AstraZeneca
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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