CA Patent

CA2758460C — Methods of preparing monodisperse oligo (ethylene glycol) reagent compositions

Assigned to Nektar Therapeutics · Expires 2014-09-23 · 12y expired

What this patent protects

Provided herein are methods for preparing monodisperse oligo (ethylene glycol) reagent compositions comprising reacting a halo-terminated oligo (ethylene glycol) with a hydroxyl-terminated oligo (ethylene glycol); also provided herein are small molecule drugs that are chemically …

USPTO Abstract

Provided herein are methods for preparing monodisperse oligo (ethylene glycol) reagent compositions comprising reacting a halo-terminated oligo (ethylene glycol) with a hydroxyl-terminated oligo (ethylene glycol); also provided herein are small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from the monodisperse compositions to produce conjugates which can exhibit a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the small molecule drug not attached to the water-soluble oligomer.

Drugs covered by this patent

Patent Metadata

Patent number
CA2758460C
Jurisdiction
CA
Classification
—
Expires
2014-09-23
Drug substance claim
No
Drug product claim
No
Assignee
Nektar Therapeutics
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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