CA Patent

CA2755561A1 — Process for the preparation of alogliptin

Assigned to Mapi Pharma Ltd · Expires 2010-09-30 · 16y expired

What this patent protects

The present invention is based on the discovery of a process for preparing pyrimidin- dione compounds, especially alogliptin and its derivatives, which comprises the reaction of a urea derivative of formula (VIII) with a malonic acid or its derivatives to form intermediates of fo…

USPTO Abstract

The present invention is based on the discovery of a process for preparing pyrimidin- dione compounds, especially alogliptin and its derivatives, which comprises the reaction of a urea derivative of formula (VIII) with a malonic acid or its derivatives to form intermediates of formulae (VII) or (VII-A), which are subsequently converted to a compound of formula (II) upon introduction of a leaving group X. Compound (II) then reacts with an amine to form compound (I), which is optionally converted to its salts of formula (IV).

Drugs covered by this patent

Patent Metadata

Patent number
CA2755561A1
Jurisdiction
CA
Classification
—
Expires
2010-09-30
Drug substance claim
No
Drug product claim
No
Assignee
Mapi Pharma Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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