CA2710725C — Protected aldehydes for use as intermediates in chemical syntheses, and processes for their preparation
Assigned to Sandoz Inc · Expires 2017-08-01 · 9y expired
What this patent protects
A para-methoxy protected benzaldehyde useful in preparation of treprostinil, and of formula: (see formula 1) is prepared by subjecting to Claisen re-arrangement a substituted benzaldehyde of formula (Ia): (see formula Ia) to form the m-hydroxy-substituted benzaldehyde of formula …
USPTO Abstract
A para-methoxy protected benzaldehyde useful in preparation of treprostinil, and of formula: (see formula 1) is prepared by subjecting to Claisen re-arrangement a substituted benzaldehyde of formula (Ia): (see formula Ia) to form the m-hydroxy-substituted benzaldehyde of formula (Ib): see formula Ib) and then reacting compound (Ib) with a p-methoxybenzyl (PMB) compound to form a PMB-substituted benzaldehyde of formula 1
Drugs covered by this patent
- Remodulin (TREPROSTINIL) · United Therap
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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