CA Patent

CA2683559C — Methods for treating cancer resistant to erbb therapeutics

Assigned to General Hospital Corp · Expires 2019-09-24 · 7y expired

What this patent protects

Provided herein are methods for treating cancer that is resistant to treatment with an anti- ErbB therapeutic agent and which is associated with an activating MET gene mutation or a MET gene amplification. The methods involve administering to a subject a combination of an anti- E…

USPTO Abstract

Provided herein are methods for treating cancer that is resistant to treatment with an anti- ErbB therapeutic agent and which is associated with an activating MET gene mutation or a MET gene amplification. The methods involve administering to a subject a combination of an anti- ErbB therapeutic and an anti-MET therapeutic. Also provided are methods for reducing ErbB mediated signaling or PI3 kinase mediated signaling in a cancer cell.

Drugs covered by this patent

Patent Metadata

Patent number
CA2683559C
Jurisdiction
CA
Classification
—
Expires
2019-09-24
Drug substance claim
No
Drug product claim
No
Assignee
General Hospital Corp
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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