CA2663116A1 — Inhibitors of bruton's tyrosine kinase
Assigned to Pharmacyclics LLC · Expires 2008-04-03 · 18y expired
What this patent protects
Disclosed herein are compounds that form covalent bonds with Bruton's tyr osine kinase (Btk). Also described are irreversible inhibitors of Btk. Metho ds for the preparation of the compounds are disclosed. Also disclosed are ph armaceutical compositions that include the compounds…
USPTO Abstract
Disclosed herein are compounds that form covalent bonds with Bruton's tyr osine kinase (Btk). Also described are irreversible inhibitors of Btk. Metho ds for the preparation of the compounds are disclosed. Also disclosed are ph armaceutical compositions that include the compounds. Methods of using the B tk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseas es or conditions.
Drugs covered by this patent
- Imbruvica (ibrutinib) · AbbVie
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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