CA2627358C — Heterocyclic modulators of atp-binding cassette transporters
Assigned to Vertex Pharmaceuticals Inc · Expires 2015-10-06 · 11y expired
What this patent protects
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). In one bro…
USPTO Abstract
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). In one broad aspect, there is disclosed a compound of the general formula (I): (see formula I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R'3, R4, and n are described herein. In a more specific embodiment, the invention relates to a compound having the following formula: (see formula II).
Drugs covered by this patent
- Kalydeco (IVACAFTOR) · Vertex Pharms Inc
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
Track this patent
Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.