CA2476201C — Modified release formulations of at least one form of tramadol
Assigned to Valeant International Bermuda · Expires 2009-09-01 · 17y expired
What this patent protects
The present invention provides for a modified release pharmaceutical composition comprising at least one form of tramadol selected from the group consisting of tramadol, enantiomers thereof, pharmaceutically acceptable sal ts thereof and combinations thereof, the composition exhi…
USPTO Abstract
The present invention provides for a modified release pharmaceutical composition comprising at least one form of tramadol selected from the group consisting of tramadol, enantiomers thereof, pharmaceutically acceptable sal ts thereof and combinations thereof, the composition exhibiting an in vitro dissolution profile (measured using the USP Basket Method at 75 rpm in 900 m l 0.1 N HCl at 37 ~C) such that after 2 hours, from about 0 % up to about 30 % (by weight) of the at least one form of tramadol is released, after 4 hours, from about 5 % to about 22 % (by weight) of the at least one form of tramado l is released, after 6 hours, from about 15 % to about 38 % (by weight) of the at least one form of tramadol is released, after 8 hours, more than about 40 % (by weight) of the at least one form of tramadol is released.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
Track this patent
Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.