CA Patent

CA2465675C — Improved particulate compositions for pulmonary delivery

Assigned to Alkermes Inc · Expires 2008-06-10 · 18y expired

What this patent protects

This invention concerns an improved particulate composition for delivering a drug to the pulmonary system. Applicants disclose a method of identifying an optimal form of aerodynamically light particles which are highly dispersible. The particles of the instant invention are made…

USPTO Abstract

This invention concerns an improved particulate composition for delivering a drug to the pulmonary system. Applicants disclose a method of identifying an optimal form of aerodynamically light particles which are highly dispersible. The particles of the instant invention are made by creating hollow, spherical drug particles (i.e., progenitor particles) that collapse in the process of particle formation, leading to wrinkled, thin-walled drug particles of very low envelope density. Additionally, applicants have found that such particles are especially optimal for inhaled aerosols when the surface area parameter (.SIGMA.) is greater than 2, optimally greater than 3.

Drugs covered by this patent

Patent Metadata

Patent number
CA2465675C
Jurisdiction
CA
Classification
—
Expires
2008-06-10
Drug substance claim
No
Drug product claim
No
Assignee
Alkermes Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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