CA2461616A1 — Composite dosage forms having an inlaid portion

USPTO Abstract

A dosage form comprises at least one active ingredient, a first portion whic h comprises an exterior surface and one or more cavities defining at least one interior surface having indentations and an exterior surface, and a second molded portion which is inlaid into the cavities of the first portion and ha s an exterior surface. The first and second portions are in contact at an interface, the second portion comprises a solidified thermoplastic material, and the second portion resides substantially conformally upon the indentatio ns of the first portion. In another embodiment, a dosage form comprises at leas t one active ingredient, a core having an outer surface and a shell residing o n at least a portion of the core outer surface, wherein the shell comprises a first shell portion and a second molded shell portion which is inlaid into t he first shell portion. In another embodiment, a dosage form comprises at least one active ingredient, a core, and a shell having a first molded shell porti on which is discontinuous, and a second molded shell portion which is continuou s, such that the discontinuities of the first shell portion are due to the presence of the second molded shell portion, and the first and second shell portions are compositionally different.