CA2387013A1 — 6-position substituted indolinones, the preparation thereof and their use as pharmaceutical compositions
Assigned to Boehringer Ingelheim Pharma GmbH and Co KG · Expires 2001-04-19 · 25y expired
What this patent protects
The invention relates to a 6-substituted indoline of formula (I), wherein R1 to R5 and X are as defined in claim 1, isomers and salts of said compound, i n particular physiologically compatible salts of said compound having pharmacologically important characteristics, in particu…
USPTO Abstract
The invention relates to a 6-substituted indoline of formula (I), wherein R1 to R5 and X are as defined in claim 1, isomers and salts of said compound, i n particular physiologically compatible salts of said compound having pharmacologically important characteristics, in particular inhibiting action on different receptor-tyrosine kinases and cyclin/CDK complexes in addition to inhibiting the proliferation of endothelial cells and different tumor cells. The invention also relates to medicaments containing said compounds, the use of said compounds and a method for the production thereof.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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