CA Patent

CA2345112A1 — Process for the preparation of (-)-a-difluoromethylornithine monohydrochloride monohydrate

Assigned to Lonza AG · Expires 2000-03-30 · 26y expired

What this patent protects

According to the invention, (+/-)-.alpha.-(difluoromethyl)ornithine is cleaved into its isomers by means of (-)-O, O'-di-p -toluyol -L-tartaric acid. (+/-) -.alpha.- (difluoromethyl)ornithine -monohydroch loride monohydrate and notably its (-)-isomer are inhibitors of orn…

USPTO Abstract

According to the invention, (+/-)-.alpha.-(difluoromethyl)ornithine is cleaved into its isomers by means of (-)-O, O'-di-p -toluyol -L-tartaric acid. (+/-) -.alpha.- (difluoromethyl)ornithine -monohydroch loride monohydrate and notably its (-)-isomer are inhibitors of ornithine decarboxylase and thus have numerous pharmacological actions.

Drugs covered by this patent

eflornithine-hydrochloride (EFLORNITHINE HYDROCHLORIDE)

Patent Metadata

Patent number: CA2345112A1
Jurisdiction: CA
Classification: —
Expires: 2000-03-30
Drug substance claim: No
Drug product claim: No
Assignee: Lonza AG
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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