CA Patent

CA2340118C — Liposomal bupivacaine compositions prepared using an ammonium sulfate gradient

Assigned to Yissum Research Development Co of Hebrew University of Jerusalem · Expires 2009-01-13 · 17y expired

What this patent protects

Liposomal bupivacaine compositions are prepared using an ammonium sulfate gradient loading procedure, at a pH which prevents precipitation of the drug from the loading solution. Also described are liposome suspensions comprising "GMV" (giant multivesicular) liposomes and …

USPTO Abstract

Liposomal bupivacaine compositions are prepared using an ammonium sulfate gradient loading procedure, at a pH which prevents precipitation of the drug from the loading solution. Also described are liposome suspensions comprising "GMV" (giant multivesicular) liposomes and methods for their preparation. The liposomal compositions are characterized by high drug-to-lipid ratios and provide long term analgesia.

Drugs covered by this patent

Patent Metadata

Patent number
CA2340118C
Jurisdiction
CA
Classification
—
Expires
2009-01-13
Drug substance claim
No
Drug product claim
No
Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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