CA Patent

CA2258683C — Oral composition comprising a triazole antifungal compound

Assigned to Merck Sharp and Dohme LLC · Expires 2007-07-31 · 19y expired

What this patent protects

A pharmaceutical composition comprising: i) substantially inert beads; where in said beads are coated with ii) an antifun- gal agent which is (-)-(2R-cis)-4-[4-[4-[4-[[-5-(2,4-difluorophenyl)- tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methoxy]phenyl]-1- piperazinyl]phe…

USPTO Abstract

A pharmaceutical composition comprising: i) substantially inert beads; where in said beads are coated with ii) an antifun- gal agent which is (-)-(2R-cis)-4-[4-[4-[4-[[-5-(2,4-difluorophenyl)- tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methoxy]phenyl]-1- piperazinyl]phenyl)-2,4-dihydro-2-[(S)-1-ethyl-2(S)-hydroxypropyl]-3H-1,2,4- triazol-3-one; iii) a binder to enable the antifungal compound to adhere to said beads. The composition enables the antifungal compound, which has very low water solubility, to have enhanced bioavail- ability in mammals, such as humans.

Drugs covered by this patent

Patent Metadata

Patent number
CA2258683C
Jurisdiction
CA
Classification
—
Expires
2007-07-31
Drug substance claim
No
Drug product claim
No
Assignee
Merck Sharp and Dohme LLC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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