CA2176712A1 — Synthetic membrane vesicles with controlled release of encapsulated biologically active substances

USPTO Abstract

A synthetic membrane vesicle composition containing at least one release-rate modifying agent other than a hydrohalide and at least one biologically active substance, the vesicles having defined size distribution, adjustable average size, internal chamber size and number and a controlled release rate of the biologically active substance. A process for making the composition features addition of a release-rate modifying agent effective to prolong, sustain, and control the rate of release from the vesicles of the biologically active substance at therapeutic levels after encapsulation.