CA Patent

CA2088503A1 — Phenolic thioetheramides as 5-lipoxygenase inhibitors

Assigned to GD Searle LLC · Expires 1992-03-08 · 34y expired

What this patent protects

The present invention relates to phenolic thioetheramides of formula (I) wherein R1 and R2 are tert-alkyl or phenyl, Alk1 and Alk2 are alkylene; X is sulfer or oxygen, m is 0, 1, or 2; and R is a) wherein R3 and R4 are hydrogen or alkyl and Alk3 is alkylene; or b) wherein Y is CH…

USPTO Abstract

The present invention relates to phenolic thioetheramides of formula (I) wherein R1 and R2 are tert-alkyl or phenyl, Alk1 and Alk2 are alkylene; X is sulfer or oxygen, m is 0, 1, or 2; and R is a) wherein R3 and R4 are hydrogen or alkyl and Alk3 is alkylene; or b) wherein Y is CH, N, O, or S; R6 is hydrogen, alkyl, phenyl, substituted phenyl, benzyl, substituted benzyl or a heterocyclic amine; and R7 is hydrogen or alkyl. The compounds inhibit 5-lipoxygenase and are useful in the treatment of inflammation and allergic conditions.

Drugs covered by this patent

Patent Metadata

Patent number
CA2088503A1
Jurisdiction
CA
Classification
—
Expires
1992-03-08
Drug substance claim
No
Drug product claim
No
Assignee
GD Searle LLC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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