CA Patent

CA2070978A1 — Cyclic renin inhibitors

Assigned to Merck and Co Inc · Expires 1992-12-12 · 33y expired

What this patent protects

TITLE OF THE INVENTION CYCLIC RENIN INHIBITORS WHICH CONTAIN 3(S)-AMINO-4-CYCLOHEXYL-2(R)-HYDROXY-BUTANOIC ACID OR 4-CYCLOHEXYL-(2R, 3S)- DIHYDROXYBUTANOIC ACID OR RELATED DIOL ANALOGS OR HYDROXYKETONE ANALOGS AND WHICH INCORPORATE L-SERINE OR RELATED ANALOGS AT THE ABSTRACT …

USPTO Abstract

TITLE OF THE INVENTION CYCLIC RENIN INHIBITORS WHICH CONTAIN 3(S)-AMINO-4-CYCLOHEXYL-2(R)-HYDROXY-BUTANOIC ACID OR 4-CYCLOHEXYL-(2R, 3S)- DIHYDROXYBUTANOIC ACID OR RELATED DIOL ANALOGS OR HYDROXYKETONE ANALOGS AND WHICH INCORPORATE L-SERINE OR RELATED ANALOGS AT THE ABSTRACT OF THE DISCLOSURE Compounds of the formula: (I) 85/MRD57 -i- 18014C are disclosed. These compounds inhibit the angioten-sinogen-cleaving action of the natural proteolytic enzyme, renin, and are useful in treating, preventing or managing renin-associated hypertension, hyperaldo-steronism, congestive heart failure, and glaucoma.

Drugs covered by this patent

Patent Metadata

Patent number
CA2070978A1
Jurisdiction
CA
Classification
—
Expires
1992-12-12
Drug substance claim
No
Drug product claim
No
Assignee
Merck and Co Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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