CA2069760A1 — Lipid Formulation System

USPTO Abstract

The invention relates to a lipid particle forming matrix, characterized by, that from a defined system of at least two lipid components chosen from classes of different polarity, in which at least one of the lipid components is bilayer forming, discrete lipid particles are formed spontaneously when interacting with aqueous systems. Preferably at least one of the lipid components is amphiphatic and polar and one is nonpolar. These discrete particles are formed spontaneously from the matrix without any chemical or physical treatment or initiation. The lipid particle forming matrix can contain bioactive materials, chosen from the group of drugs, herbicides, pesticides, fertilizers, food and cosmetic ingredients or additives. The invention also relates to a process for the production of the matrix, the use of the lipid particle forming matrix as a carrier system for bioactive materials and pharmaceutical composition such as oral, rectal, nasal, vaginal, ocular or parenteral vehicles, creams, ointments, capsules and tablets containing the said lipid particle forming matrix and a drug.