CA2047029A1 — Microbial transformation process for antihypertensive products
Assigned to Merck and Co Inc · Expires 1992-01-20 · 34y expired
What this patent protects
TITLE OF THE INVENTION MICROBIAL TRANSFORMATION PROCESS FOR ANTIHYPERTENSIVE PRODUCTS ABSTRACT OF THE DISCLOSURE Fermentation of the microorganism Streptomyces sp. MA6751 (ATCC No. 55043) in the presence of the Angiotensin II (A II) receptor antagonist (II) 12/…
USPTO Abstract
TITLE OF THE INVENTION MICROBIAL TRANSFORMATION PROCESS FOR ANTIHYPERTENSIVE PRODUCTS ABSTRACT OF THE DISCLOSURE Fermentation of the microorganism Streptomyces sp. MA6751 (ATCC No. 55043) in the presence of the Angiotensin II (A II) receptor antagonist (II) 12/CSQ2 - i - 18157 yields an N2-tetrazole .beta.-glucuronide analog which is also an A II antagonist useful in the treatment of hypertension and congestive heart failure and other indications known to respond to A II antagonists.
Drugs covered by this patent
- Trulance (PLECANATIDE) · Salix
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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