CA1282405C — Method for making uniformly sized particles from water-insoluble organic compounds
Assigned to Sterilization Technical Services Inc · Expires 1991-04-02 · 35y expired
What this patent protects
METHOD FOR MAKING UNIFORMLY SIZED PARTICLES FROM WATER-INSOLUBLE ORGANIC COMPOUNDS ABSTRACT OF THE DISCLOSURE The invention involves a method for making uniformly sized particles from water-insoluble drugs or other organic compounds. First, a suitable s…
USPTO Abstract
METHOD FOR MAKING UNIFORMLY SIZED PARTICLES FROM WATER-INSOLUBLE ORGANIC COMPOUNDS ABSTRACT OF THE DISCLOSURE The invention involves a method for making uniformly sized particles from water-insoluble drugs or other organic compounds. First, a suitable solid organic compound is dissolved in an organic solvent, and the solution can be diluted with a non-solvent. Then, an aqueous precipitating liquid is infused, precipitating non-aggregated particles with substantially uniform mean diameter. The particles are then separated from the organic solvent. Depending on the organic compound and the desired particle size, the parameters of temperature, ratio of non-solvent to organic solvent, infusion rate, stir rate, and volume can be varied according to the invention.
Drugs covered by this patent
- Ztalmy (GANAXOLONE) · Marinus
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
Track this patent
Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.