CA1147342A — Process of producing novel phenylethanolamine derivatives

USPTO Abstract

ABSTRACT Process of producing novel phenylethanolamine derivatives represented by the formula: wherein R represents hydrogen atom, halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, an amino group, a lower acylamino group, a lower alkylsulfonyl group, or a lower alkylsulfonylamino group; R1, R2, R3 and R4, which may be the same or different, each represents hydrogen atom or a lower alkyl group; R5 represents an unsubstituted or substituted aryl group, a benzodioxane ring group, an aryloxy group or an arylthio group; said R5 being, however, an unsubstituted or substituted benzodioxane ring group, an aryloxy group or an arylthio group when R is hydroxyl group; and n represents 0 or an integer of 1-3 and the acid addition salts thereof. The coopounds of this invention exhibit .alpha.- and .beta. -adrenergic blocking actions and are useful as antihypertensive agent.