AU Patent

AU679566B2 — Amine-derivatized nucleosides and oligonucleosides

Assigned to Ionis Pharmaceuticals Inc · Expires 1997-07-03 · 29y expired

What this patent protects

Oligonucleotide-folate conjugates are described wherein folates are conjugated to one or more sites on an oligonucleotide including the 2'-, 3'-, 5'-, nucleobase and internucleotide linkage sites. The folate can be attached via the alpha- or gamma-carboxylate, optionally through …

USPTO Abstract

Oligonucleotide-folate conjugates are described wherein folates are conjugated to one or more sites on an oligonucleotide including the 2'-, 3'-, 5'-, nucleobase and internucleotide linkage sites. The folate can be attached via the alpha- or gamma-carboxylate, optionally through a linking group. Methods for the regiospecific synthesis of the conjugates are disclosed.

Drugs covered by this patent

Patent Metadata

Patent number
AU679566B2
Jurisdiction
AU
Classification
—
Expires
1997-07-03
Drug substance claim
No
Drug product claim
No
Assignee
Ionis Pharmaceuticals Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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