AU Patent

AU2758899A — Process for the enzymatic resolution of lactams

Assigned to GD Searle LLC · Expires 1999-08-30 · 27y expired

What this patent protects

A method of separating enantiomeric lactam esters. The lactam esters are contacted with a biocatalyst, such as an enzyme or a microorganism, in a solution wherein only one enantiomer is selectively hydrolyzed to give the optically active isomer of the corresponding acid. The hydr…

USPTO Abstract

A method of separating enantiomeric lactam esters. The lactam esters are contacted with a biocatalyst, such as an enzyme or a microorganism, in a solution wherein only one enantiomer is selectively hydrolyzed to give the optically active isomer of the corresponding acid. The hydrolysis product is then separated from the unreacted lactam esters. The enzyme is then recycled for reuse in the next enzymatic resolution. The undesired isomer is also racemized and reused in the next enzymatic resolution.

Drugs covered by this patent

Patent Metadata

Patent number
AU2758899A
Jurisdiction
AU
Classification
—
Expires
1999-08-30
Drug substance claim
No
Drug product claim
No
Assignee
GD Searle LLC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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