AU2024202868A1 — Hydrazide containing nuclear transport modulators and uses thereof
Assigned to Karyopharm Therapeutics Inc · Expires 2024-05-23 · 2y expired
What this patent protects
OF THE INVENTION The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by stctural formula I: N-N ) NH I, O N-R2 F 3C N R R3 CF 3 (I, or a pharmaceutically acceptable salt thereof, wherein …
USPTO Abstract
OF THE INVENTION The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by stctural formula I: N-N ) NH I, O N-R2 F 3C N R R3 CF 3 (I, or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
Track this patent
Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.