AU2022259816B2 — Drug eluting ocular implant

USPTO Abstract

#$%^&*AU2022259816B220250828.pdf##### C:\Users\ljr\AppData\Roa.ing\iManagc\Work\Recent\35544550AU Drugcutnocular mpIant\Disional spc pags (SOI andcla, is) forfurtherdiv(23642928.1).doex-27/10/2022 Abstract A drug delivery ocular implant comprising: an outer shell shaped to define an interior space, the outer shell having a sidewall, one closed distal end, and one open proximal end; a drug contained within the interior space; a membrane proximate the open proximal end, the membrane being permeable or semi-permeable to the drug; a cap dimensioned to fit within or over the one open end; and an anchor on the closed distal end; wherein the cap secures the membrane to the outer shell while providing at least one opening to allow the drug to elute from the implant through the membrane to an anterior chamber of an eye, wherein the at least one opening of the cap and the membrane together control a rate of elution of the drug from the implant through the membrane and the at least one opening of the cap; wherein the cap comprises at least one region that is compressible such that the cap is securely sealed to the outer shell. 91 C:\Users\jr\AppData\Roaming\iManagc\Work\Rccent\35544550AU Drug cluting ocular implant\Divisional spec pages (SOI and claims) for further div(23642928.1).docx-27/10/2022 Abstract 2022259816 27 Oct 2022 A drug delivery ocular implant comprising: an outer shell shaped to define an interior space, the outer shell having a sidewall, one closed distal end, and one open proximal end; a drug contained within the interior space; a membrane proximate the open proximal end, the membrane being permeable or semi-permeable to the drug; a cap dimensioned to fit within or over the one open end; and an anchor on the closed distal end; wherein the cap secures the membrane to the outer shell while providing at least one opening to allow the drug to elute from the implant through the membrane to an anterior chamber of an eye, wherein the at least one opening of the cap and the membrane together control a rate of elution of the drug from the implant through the membrane and the at least one opening of the cap; wherein the cap comprises at least one region that is compressible such that the cap is securely sealed to the outer shell. 91