AU2021480621A1 — Compositions containing fexofenadine

USPTO Abstract

The disclosure is directed to processes of preparing a spray-dried formulation comprising fexofenadine zwitterion dihydrate comprising spray-drying (i) a fexofenadine zwitterion dihydrate composition; and (ii) an inert matrix. Also provided by the disclosure are products prepared according to the processes described herein, spray-dried formulations comprising fexofenadine zwitterion dihydrate and an inert matrix, oral solid dosage forms comprising the spray-dried formulation described herein, and methods of relieving symptoms due to an allergy in a patient in need thereof, comprising administering a therapeutically effective amount of the spray-dried formulation or oral solid dosage form described herein to the patient.