AU2018205090A1 — Carbohydrate conjugates as delivery agents for oligonucleotides
Assigned to Alnylam Pharmaceuticals Inc · Expires 2018-07-26 · 8y expired
What this patent protects
Abstract The invention relates to a modified oligonucleotide comprising a structure shown below: Linker-LG Linker-LG Linker-LG 5 Linker-LG, Linker-LG, Linker-LG Linker-LG Linker-LG GG or Linker-LG LG is independently for each occurrence a ligand; and Z', Z", Z"' and Z"…
USPTO Abstract
Abstract The invention relates to a modified oligonucleotide comprising a structure shown below: Linker-LG Linker-LG Linker-LG 5 Linker-LG, Linker-LG, Linker-LG Linker-LG Linker-LG GG or Linker-LG LG is independently for each occurrence a ligand; and Z', Z", Z"' and Z"" are each independently for each occurrence 0 or S; and wherein all of the nucleotide 10 sugars of the RNA agent is modified, and to a method of modulating expression of a target gene using the modified oligonucleotide. 5622837_1 (GHMatters) P84321.AU.1 PETERB 31/07/14
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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