AU2016225781A1 — Radioactive fluorine labeling precursor compound and method for manufacturing radioactive fluorine labeled compound using the same

USPTO Abstract

- 60 There is provided a labeling precursor compound represented by the following general formula (2): R2 R 3 (2) ON .S R7 n 02 wherein R1 represents an alkynyl group, an alkynyloxy group, an azide group, an azidoalkyl group, an arylazide group, a monocyclic or condensed polycyclic aryl group or a nitrogen-containing heterocycle; R2 and R3 each 10 independently represent an alkyl group or a hydroxyalkyl group which hydroxy group may be protected with a protecting group, and n is an integer of 1 or 2; R6 represents an alkyl group or -CONR 1 1 R 1 2 wherein R 11 and R1 2 each independently represent an alkyl group or a 15 monocyclic or condensed polycyclic aryl group; and R4, R5 , R 7 and R8 each independently represent a hydrogen atom, an alkyl group or an alkoxy group.