AU2016204652C1 — Compositions and methods for lowering triglycerides without raising ldl-c levels
Assigned to Amarin Pharmaceuticals Ireland Ltd · Expires 2018-08-09 · 8y expired
What this patent protects
A method of lowering triglycerides in a subject on stable statin therapy having baseline fasting triglycerides of about 200 mg/dl to about 500 mg/dl, the method comprising administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of ultra-pure EP…
USPTO Abstract
A method of lowering triglycerides in a subject on stable statin therapy having baseline fasting triglycerides of about 200 mg/dl to about 500 mg/dl, the method comprising administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of ultra-pure EPA per day, wherein (1) upon administering the composition to the subject daily for a period of 12 weeks the subject exhibits at least 5% lower fasting triglycerides than a placebo controlled subject maintained on stable statin therapy without concomitant ultra- pure EPA for a period of 12 weeks, (2) the subject exhibits substantially no serum LDL-C increase, and (3) the placebo controlled subject also has baseline fasting triglycerides of about 200 mg/dl to about 500 mg/dl.
Drugs covered by this patent
- Vascepa (ICOSAPENT ETHYL) · Amarin Pharms
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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