AU2014280956B2 — Chemically modified small molecules
Assigned to Nektar Therapeutics · Expires 2016-09-22 · 10y expired
What this patent protects
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer obtained from a monodisperse or bimodal water-soluble oligomer composition, A conjugate of the invention, when administered by any of a number of administra…
USPTO Abstract
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer obtained from a monodisperse or bimodal water-soluble oligomer composition, A conjugate of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the small molecule drug not attached to the water-soluble oligomer.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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