AU2013203566B2 — Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
Assigned to Onyx Therapeutics Inc · Expires 2016-10-13 · 10y expired
What this patent protects
The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones 5 are stereoselectivel…
USPTO Abstract
The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones 5 are stereoselectively converted to the desired keto epoxides.
Drugs covered by this patent
- Kyprolis (carfilzomib) · Amgen
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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