AU2010245545A1 — Diamino heterocyclic carboxamide compound

USPTO Abstract

Disclosed are a compound represented by formula (I) or a salt thereof; a kinase inhibitor for EML4-ALK fusion protein containing the compound; and use of the compound for the treatment of cancers. (In formula (I), -X- represents a group represented by formula (II) or formula (III); A represents –H, a halogen atom, a lower alkyl group, a cycloalkyl group or a lower alkenyl group; R represents a substituted phenyl group, a (substituted) heterocyclic group or a (substituted) bicyclic fused ring; R represents a (substituted) cycloalkyl group, a (substituted) non-aromatic heterocyclic group, a (substituted) phenyl group, a (substituted) pyridyl group or a (substituted) lower alkyl group; and R represents –H or a lower alkyl group; or alternatively R and R may combine together to form a cyclic amino group.)