AU2008283357B2 — Pharmaceutical composition containing optically active compound having thrombopoietin receptor agonist activity and intermediate thereof

USPTO Abstract

Disclosed is an optically active 4-phenylthiazole derivative having a thrombopoietin receptor agonist activity. Also disclosed is a pharmaceutical composition containing such a compound as an active ingredient, which makes an orally administrable platelet production control agent. Specifically disclosed is a pharmaceutical composition containing, as an active ingredient, an optically active compound represented by the formula below, a pharmaceutically acceptable salt thereof, or a solvate of any of them. (In the formula, R represents a halogen atom or a C-C alkyloxy group; R represents a C-C alkyl group; R represents a C-C alkyl group; R and R independently represent a fluorine atom or a chlorine atom; R represents a C-C alkyl group or a C-C alkyloxy group; and * represents an asymmetric carbon atom.)