AU2007282224B2 — Methods and means for treating DNA repeat instability associated genetic disorders
Assigned to Vico Therapeutics BV · Expires 2013-08-29 · 13y expired
What this patent protects
The current invention provides for methods and medicaments that apply oligonucleotide molecules complementary onl y to a repetitive sequence in a human gene transcript, for the manufacture of a medicament for the diagnosis, treatment or prevention of a cis-element repeat instabil…
USPTO Abstract
The current invention provides for methods and medicaments that apply oligonucleotide molecules complementary onl y to a repetitive sequence in a human gene transcript, for the manufacture of a medicament for the diagnosis, treatment or prevention of a cis-element repeat instability associated genetic disorders in humans. The invention hence provides a method of treatment for cis-element repeat instability associated genetic disorders. The invention also pertains to modified oligonucleotides which can be applied in method of the invention to prevent the accumulation and/or translation of repeat expanded transcripts in cells.
Drugs covered by this patent
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