Generic entry timeline

VOSORITIDE generics — when can they launch?

VOSORITIDE (VOSORITIDE) · · 24 active US patents · 0 expired

Earliest patent expiry
2030-05-20
4 years remaining
Full patent estate to
2042-07-11
complete protection through 2042
FDA approval
2021

Where VOSORITIDE sits in the generic timeline

Mid-term cliff: earliest active US patent for VOSORITIDE expires in 2030 (~4 years). Generic developers typically begin ANDA bioequivalence studies 3-4 years ahead of this date. Paragraph IV filings + Hatch-Waxman 30-month stays may shift the effective entry by another 18-36 months.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Method of Use — 21 patents
  • Formulation — 3 patents

FDA U-codes carved out by VOSORITIDE patents

Method-of-use patents are listed against specific FDA Patent Use Codes ("U-codes") representing carved-out indications. Generics can launch with a label that omits these uses.

U-codeDescription
U-3927(no description)

Sample patent estate

Showing 6 of 24 active US patents. View full estate on the VOSORITIDE drug page →

  • USRE48267 Method of Use · expires 2030-05-20
    This patent, US RE48267, protects a specific method of using the drug vosoritide.
  • USRE48267 Method of Use · expires 2030-05-20
    This patent, US RE48267, protects a specific method of using the drug vosoritide.
  • USRE48267 Method of Use · expires 2030-05-20
    This patent, US RE48267, protects a specific method of using the drug vosoritide.
  • US8198242 Method of Use · expires 2030-06-11
    This patent protects variants of C-type natriuretic peptide and methods of making them for use as therapeutic agents in treating bone-related disorders and vascular smooth muscle disorders.
    USPTO title: Variants of C-type natriuretic peptide
  • US8198242 Method of Use · expires 2030-06-11
    This patent protects variants of C-type natriuretic peptide and methods of making them for use as therapeutic agents in treating bone-related disorders and vascular smooth muscle disorders.
    USPTO title: Variants of C-type natriuretic peptide
  • US8198242 Method of Use · expires 2030-06-11
    This patent protects variants of C-type natriuretic peptide and methods of making them for use as therapeutic agents in treating bone-related disorders and vascular smooth muscle disorders.
    USPTO title: Variants of C-type natriuretic peptide

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

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