Generic entry timeline

VARENICLINE TARTRATE generics — when can they launch?

VARENICLINE TARTRATE (VARENICLINE TARTRATE) · · 10 active US patents · 0 expired

Earliest patent expiry
2035-10-19
9 years remaining
Full patent estate to
2035-10-19
complete protection through 2035
FDA approval
2006

Where VARENICLINE TARTRATE sits in the generic timeline

Long-dated protection: earliest active US patent for VARENICLINE TARTRATE extends to 2035 (~9 years out). Generic competition is at least 4 years away. Lifecycle moves (new formulations, label extensions, combination filings) typically execute 18-36 months ahead of cliff.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Method of Use — 8 patents
  • Formulation — 2 patents

FDA U-codes carved out by VARENICLINE TARTRATE patents

Method-of-use patents are listed against specific FDA Patent Use Codes ("U-codes") representing carved-out indications. Generics can launch with a label that omits these uses.

U-codeDescription
U-1900(no description)

Sample patent estate

Showing 6 of 10 active US patents. View full estate on the VARENICLINE TARTRATE drug page →

  • US10456396 Method of Use · expires 2035-10-19
    This patent protects methods and pharmaceutical formulations for treating dry eye disease.
    USPTO title: Dry eye treatments
  • US11903942 Formulation · expires 2035-10-19
    This patent protects methods and pharmaceutical formulations for treating dry eye disease using varenicline.
    USPTO title: Compositions and use of varenicline for treating dry eye
  • US9504645 Formulation · expires 2035-10-19
    This patent protects pharmaceutical formulations for treating ocular conditions.
    USPTO title: Pharmaceutical formulations for treating ocular conditions
  • US11911380 Method of Use · expires 2035-10-19
    This patent protects methods and pharmaceutical formulations for treating dry eye disease using varenicline.
    USPTO title: Compositions and use of varenicline for treating dry eye
  • US11903943 Method of Use · expires 2035-10-19
    This patent protects methods and pharmaceutical formulations for treating dry eye disease using varenicline.
    USPTO title: Compositions and use of varenicline for treating dry eye
  • US11224598 Method of Use · expires 2035-10-19
    This patent protects methods and pharmaceutical formulations for treating dry eye disease.
    USPTO title: Methods of increasing lacrimal proteins

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

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