Generic entry timeline

PIMAVANSERIN TARTRATE generics — when can they launch?

PIMAVANSERIN TARTRATE (PIMAVANSERIN TARTRATE) · · 27 active US patents · 0 expired

Earliest patent expiry
2026-08-24
expired
Full patent estate to
2039-02-27
complete protection through 2039
FDA approval
2016

Where PIMAVANSERIN TARTRATE sits in the generic timeline

All listed Orange Book patents for PIMAVANSERIN TARTRATE have expired. Generic entry is permitted, and ANDA filers can launch without patent infringement risk. Hatch-Waxman exclusivity (NCE/ODE/PED) may still apply if recently approved.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Other — 12 patents
  • Method of Use — 6 patents
  • Composition of Matter — 6 patents
  • Formulation — 3 patents

FDA U-codes carved out by PIMAVANSERIN TARTRATE patents

Method-of-use patents are listed against specific FDA Patent Use Codes ("U-codes") representing carved-out indications. Generics can launch with a label that omits these uses.

U-codeDescription
U-1844(no description)
U-1974(no description)

Sample patent estate

Showing 6 of 27 active US patents. View full estate on the PIMAVANSERIN TARTRATE drug page →

  • US7659285 Method of Use · expires 2026-08-24
    This patent protects a method of using a selective serotonin 2A/2C receptor inverse agonist, such as pimavanserin tartrate, to treat neurodegenerative diseases.
    USPTO title: Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
  • US7659285 Method of Use · expires 2026-08-24
    This patent protects a method of using a selective serotonin 2A/2C receptor inverse agonist, such as pimavanserin tartrate, to treat neurodegenerative diseases.
    USPTO title: Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
  • US7659285 Method of Use · expires 2026-08-24
    This patent protects a method of using a selective serotonin 2A/2C receptor inverse agonist, such as pimavanserin tartrate, to treat neurodegenerative diseases.
    USPTO title: Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
  • US7732615 Composition of Matter · expires 2028-06-03
    This patent protects methods for synthesizing Pimavanserin Tartrate, its hemi-tartrate salt, and various crystalline forms of the substance.
    USPTO title: N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
  • US7732615 Composition of Matter · expires 2028-06-03
    This patent protects methods for synthesizing Pimavanserin Tartrate, its hemi-tartrate salt, and various crystalline forms of the substance.
    USPTO title: N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
  • US7732615 Composition of Matter · expires 2028-06-03
    This patent protects methods for synthesizing Pimavanserin Tartrate, its hemi-tartrate salt, and various crystalline forms of the substance.
    USPTO title: N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

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