Generic entry timeline

Nourianz generics — when can they launch?

Nourianz (ISTRADEFYLLINE) · Kyowa Kirin · 4 active US patents · 0 expired

Earliest patent expiry
2027-09-05
1 year remaining
Full patent estate to
2028-01-28
complete protection through 2028
FDA approval
2019
Kyowa Kirin

Where Nourianz sits in the generic timeline

Imminent generic cliff: earliest active US patent for Nourianz expires in 2027 (~1 year from today). ANDA filers are likely already preparing Paragraph IV certifications. Expect first-filer 180-day exclusivity competition imminently.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Formulation — 2 patents
  • Method of Use — 2 patents

FDA U-codes carved out by Nourianz patents

Method-of-use patents are listed against specific FDA Patent Use Codes ("U-codes") representing carved-out indications. Generics can launch with a label that omits these uses.

U-codeDescription
U-2623(no description)

Sample patent estate

Showing 4 of 4 active US patents. View full estate on the Nourianz drug page →

  • US8318201 Formulation · expires 2027-09-05
    This patent protects a method for stabilizing a diarylvinylene compound in a solid formulation.
    USPTO title: Method of stabilizing diarylvinylene compound
  • US8318201 Formulation · expires 2027-09-05
    This patent protects a method for stabilizing a diarylvinylene compound in a solid formulation.
    USPTO title: Method of stabilizing diarylvinylene compound
  • US7727993 Method of Use · expires 2028-01-28
    This patent protects methods of treating movement disorders, including reducing side effects of Parkinson's disease therapy, by administering adenosine A2A receptor antagonists.
    USPTO title: Administering adenosine A2A receptor antagonist to reduce or suppress side effects of parkinson's disease therapy
  • US7727993 Method of Use · expires 2028-01-28
    This patent protects methods of treating movement disorders, including reducing side effects of Parkinson's disease therapy, by administering adenosine A2A receptor antagonists.
    USPTO title: Administering adenosine A2A receptor antagonist to reduce or suppress side effects of parkinson's disease therapy

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

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